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From mechanisms to therapies: current advances breakthroughs in alopecia areata immunopathology

Alopecia areata (AA) is a prevalent autoimmune condition characterized by hair loss, with the collapse of hair follicle immune privilege being a pivotal event in its pathogenesis. This collapse involves intricate immunological disturbances, where CD8+NKG2D+ T cells, driven by inflammatory cytokines...

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Principais autores: Huai-Bo Zhao, Ya-Nan Zhang, Yan Qiang, Guo-Mi Wang, Li-Wei Wang, Wen-Cheng Jiang, Xi Chen
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2025-09-01
סדרה:Frontiers in Immunology
נושאים:
alopecia areata
hair follicle immune privilege collapse
autoimmune
immunotherapy
targeted therapy
גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1621492/full
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