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DNA Methylation Algorithms of Aging and Incident Cardiovascular Disease: A Prospective Cohort Study

Background While DNA methylation (DNAm)‐based algorithms of aging show promise for predicting age‐related diseases, their comparative utility for incident cardiovascular disease (CVD) remains underexplored. We aimed to systematically compare 13 DNAm algorithms in relation to CVD risk in older adults...

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Principais autores: Xian Cui, Chunbei Yi, Hui Zhang, Yaqian Xu, Chongyu Ding, Zhaojun Wang, Shiqun Sun, Xiangwei Li
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2025-12-01
Serier:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Fag:
age acceleration
cardiovascular disease
DNA methylation
epigenetic clock
incident
Online adgang:https://www.ahajournals.org/doi/10.1161/JAHA.125.045545
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