Detection of cryptogenic malignancies from metagenomic whole genome sequencing of body fluids

Abstract Background Metagenomic next-generation sequencing (mNGS) of body fluids is an emerging approach to identify occult pathogens in undiagnosed patients. We hypothesized that metagenomic testing can be simultaneously used to detect malignant neoplasms in addition to infectious pathogens. Method...

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Hlavní autoři:	Wei Gu, Eric Talevich, Elaine Hsu, Zhongxia Qi, Anatoly Urisman, Scot Federman, Allan Gopez, Shaun Arevalo, Marc Gottschall, Linda Liao, Jack Tung, Lei Chen, Harumi Lim, Chandler Ho, Maya Kasowski, Jean Oak, Brittany J. Holmes, Iwei Yeh, Jingwei Yu, Linlin Wang, Steve Miller, Joseph L. DeRisi, Sonam Prakash, Jeff Simko, Charles Y. Chiu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2021-06-01
Edice:	Genome Medicine
On-line přístup:	https://doi.org/10.1186/s13073-021-00912-z
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