The Р60-S6K1 isoform of ribosomal protein S6 kinase 1 is a product of alternative mRNA translation

Ribosomal protein S6 kinase 1 (S6K1) is a well-known downstream effector of mTORC1 (mechanistic target of rapamycin complex 1) participating primarily in the regulation of cell growth and metabolism. Deregulation of mTOR/S6K1 signaling can promote numerous human pathologies, including cancer, neurod...

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Autors principals:	I. V. Zaiets, A. S. Sivchenko, A. I. Khoruzhenko, L. O. Savinska, V. V. Filonenko
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2018-07-01
Col·lecció:	The Ukrainian Biochemical Journal
Matèries:	Akt/mTOR/S6K1 signaling pathway CRISPR/Cas9 technology p60-S6 kinase 1 (p60-S6K1) isoform
Accés en línia:	http://ukrbiochemjournal.org/2018/06/the-%d1%8060-s6k1-isoform-of-ribosomal-protein-s6-kinase-1-is-a-product-of-alternative-mrna-translation.html
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