Inhibition of hyaluronan synthesis reduces versican and fibronectin levels in trabecular meshwork cells.
Hyaluronan (HA) is a major component of the extracellular matrix (ECM) and is synthesized by three HA synthases (HAS). Similarities between the HAS2 knockout mouse and the hdf mutant mouse, which has a mutation in the versican gene, suggest that HA and versican expression may be linked. In this stud...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2012-01-01
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| Serija: | PLoS ONE |
| Online dostop: | http://europepmc.org/articles/PMC3489675?pdf=render |
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