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RGS10 attenuates systemic immune dysregulation induced by chronic inflammatory stress

Abstract Regulator of G-protein signaling 10 (RGS10), a key homeostatic regulator of immune cells, has been implicated in multiple diseases associated with aging and chronic inflammation including Parkinson’s Disease (PD). Interestingly, subjects with idiopathic PD display reduced levels of RGS10 in...

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Furkejuvvon:
Váldodahkkit: Janna E. Jernigan, Hannah A. Staley, Zachary Baty, MacKenzie L. Bolen, Beatriz Nuñes Gomes, Jenny Holt, Cassandra L. Cole, Noelle K. Neighbarger, Kruthika Dheeravath, Andrea R. Merchak, Kelly B. Menees, Stephen A. Coombes, Malú Gámez Tansey
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: BMC 2025-02-01
Ráidu:Journal of Neuroinflammation
Fáttát:
Regulator of G protein signaling 10 (RGS10)
Chronic systemic inflammation
Immune dysregulation
Neuroinflammation
Neurodegenerative diseases
Parkinson’s disease
Liŋkkat:https://doi.org/10.1186/s12974-024-03322-1
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