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A specific dispiropiperazine derivative that arrests cell cycle, induces apoptosis, necrosis and DNA damage

Abstract Dispiropiperazine compounds are a class of molecules known to confer biological activity, but those that have been studied as cell cycle regulators are few in number. Here, we report the characterization and synthesis of two dispiropiperazine derivatives: the previously synthesized spiro[2′...

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Principais autores: Victor P. Liu, Wai-Ming Li, Jack Lofroth, Mehreen Zeb, Brian O. Patrick, Tina M. Bott, Chow H. Lee
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2023-05-01
Series:Scientific Reports
Acceso en liña:https://doi.org/10.1038/s41598-023-35927-6
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