NAC couples protein synthesis with nascent polypeptide myristoylation on the ribosome

Abstract N-glycine myristoylation allows for reversible association of newly synthesized proteins with membranes to regulate essential functions such as cellular signaling and stress responses. This process can be catalyzed during protein synthesis by N-myristoyltransferases (NMTs), and its dysregul...

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Autors principals:	Sara Zdancewicz, Emir Maldosevic, Kinga Malezyna, Ahmad Jomaa
Format:	Artigo
Idioma:	Inglês
Publicat:	Springer Nature 2025-08-01
Col·lecció:	The EMBO Journal
Matèries:	NMT2 Translating Ribosome NAC N-myristoyltransferases Nascent Chain Cryo-EM
Accés en línia:	https://doi.org/10.1038/s44318-025-00548-4
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