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Activation of TREK‐1 and TREK‐2 Two‐Pore Domain Potassium Channels by the Kv4 Channel Modulator, NS5806

ABSTRACT NS5806 is a diaryl‐urea small molecule developed for the treatment of pain and neurological disorders. A potent activator of Kv4.3 potassium channels, it is widely used to study Kv4 channel physiology in excitable cells, including trigeminal neurons. Surprisingly, we found that NS5806 produ...

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Xehetasun bibliografikoak
Egile Nagusiak: E. L. Veale, P. M. Matthews, A. M. Rush, E. B. Stevens, A. Mathie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Wiley 2026-06-01
Saila:Pharmacology Research & Perspectives
Gaiak:
Sarrera elektronikoa:https://doi.org/10.1002/prp2.70264
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