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Allosteric activation of RhlB by RNase E induces partial duplex opening in substrate RNA

The E. coli DEAD-Box helicase RhlB is responsible for ATP-dependent unwinding of structured mRNA to facilitate RNA degradation by the protein complex degradosome. The allosteric interaction with complex partner RNase E is necessary to stimulate both, RhlB’s ATPase and RNA unwinding activity to level...

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Autori principali: Heidi Zetzsche, Laura Raschke, Boris Fürtig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-08-01
Serie:Frontiers in Molecular Biosciences
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Accesso online:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1139919/full
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