The distinct clinical trajectory, metastatic sites, and immunobiology of microsatellite-instability-high cancers

Microsatellite-instability-high (MSI-H) cancers form a spectrum of solid organ tumors collectively known as Lynch Syndrome cancers, occurring not only in a subset of colorectal, endometrial, small bowel, gastric, pancreatic, and biliary tract cancers but also in prostate, breast, bladder, and thyroi...

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Principais autores:	Shuting Han, Aik Yong Chok, Daniel Yang Yao Peh, Joshua Zhi-Ming Ho, Emile Kwong Wei Tan, Si-Lin Koo, Iain Bee-Huat Tan, Johnny Chin-Ann Ong
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2022-12-01
Series:	Frontiers in Genetics
Assuntos:	microsatellite instability cancer colorectal cancer immunobiology mismatch repair (MMR)
Acceso en liña:	https://www.frontiersin.org/articles/10.3389/fgene.2022.933475/full
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