QR-Code

Enhanced antitumor immunity through sequential targeting of PI3Kδ and LAG3

Background Despite striking successes, immunotherapies aimed at increasing cancer-specific T cell responses are unsuccessful in most patients with cancer. Inactivating regulatory T cells (Treg) by inhibiting the PI3Kδ signaling enzyme has shown promise in preclinical models of tumor immunity and is...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Emma Jones, Andrew Godkin, Sarah Nicol Lauder, Kathryn Smart, Veerle Kersemans, Danny Allen, Jake Scott, Ana Pires, Stefan Milutinovic, Michelle Somerville, Sean Smart, Paul Kinchesh, Elena Lopez-Guadamillas, Ellyn Hughes, Martin Scurr, Lori S Friedman, Bart Vanhaesebroeck, Awen Gallimore
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2020-10-01
Schriftenreihe:Journal for ImmunoTherapy of Cancer
Online-Zugang:https://jitc.bmj.com/content/8/2/e000693.full
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge