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Genetic Markers and Danger Signals in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening adverse reactions, which could be induced by a variety of drugs. It was proposed that human leukocyte antigen (HLA)-restricted presentation of antigens (drugs or their metabolites) to T lymphocytes initiates the...

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Hlavní autoři: Wen-Hung Chung, Shuen-Iu Hung
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2010-01-01
Edice:Allergology International
Témata:
drug hypersensitivity
genetic polymorphism
NK cells
Stevens-Johnson syndrome
toxic epidermal necrolysis
On-line přístup:http://www.sciencedirect.com/science/article/pii/S1323893015306432
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