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Using single nucleotide variations in single-cell RNA-seq to identify subpopulations and genotype-phenotype linkage

Identification of cell subpopulations using transcript abundance is noisy. Here, the authors developed a linear modeling framework, SSrGE, which utilizes effective and expressed nucleotide variations from single-cell RNA-seq to identify tumor subpopulations.

Sábháilte in:
Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Olivier Poirion, Xun Zhu, Travers Ching, Lana X. Garmire
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: Nature Portfolio 2018-11-01
Sraith:Nature Communications
Rochtain ar líne:https://doi.org/10.1038/s41467-018-07170-5
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