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161533 TriKE stimulates NK-cell function to overcome myeloid-derived suppressor cells in MDS

Abstract: Myelodysplastic syndrome (MDS) is a clonal heterogeneous stem cell disorder driven by multiple genetic and epigenetic alterations resulting in ineffective hematopoiesis. MDS has a high frequency of immune suppressors, including myeloid-derived suppressor cells (MDSCs), that collectively re...

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Bibliografski detalji
Glavni autori: Dhifaf Sarhan, Ludwig Brandt, Martin Felices, Karolin Guldevall, Todd Lenvik, Peter Hinderlie, Julie Curtsinger, Erica Warlick, Stephen R. Spellman, Bruce R. Blazar, Daniel J. Weisdorf, Sarah Cooley, Daniel A. Vallera, Björn Önfelt, Jeffrey S. Miller
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2018-06-01
Serija:Blood Advances
Online pristup:http://www.sciencedirect.com/science/article/pii/S2473952920309708
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