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Autophagic degradation of CDK4 is responsible for G0/G1 cell cycle arrest in NVP-BEZ235-treated neuroblastoma

Background CDK4 is highly expressed and associated with poor prognosis and decreased survival in advanced neuroblastoma (NB). Targeting CDK4 degradation presents a potentially promising therapeutic strategy compared to conventional CDK4 inhibitors. However, the autophagic degradation of the CDK4 pro...

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Autors principals: Zhen Liu, Xiao-Yang Wang, Han-Wei Wang, Shan-Ling Liu, Chao Zhang, Feng Liu, Ying Guo, Feng-Hou Gao
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis Group 2024-12-01
Col·lecció:Cancer Biology & Therapy
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Accés en línia:https://www.tandfonline.com/doi/10.1080/15384047.2024.2385517
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