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Patients with Irritable Bowel Syndrome Exhibit Aberrant Expression of Endogenous Retroviruses and SETDB1

Irritable bowel syndrome (IBS) is a common disease, whose etiopathogenesis is poorly understood. Human endogenous retroviruses (HERVs) originate from ancient infections of germinal cells and represent 8% of our DNA. Most HERVs have become defective due to the accumulated mutations; some can, however...

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Main Authors: Pier-Angelo Tovo, Davide Giuseppe Ribaldone, Gian Paolo Caviglia, Cristina Calvi, Paola Montanari, Marco Tizzani, Demis Pitoni, Simone Frara, Elisa Tribocco, Stefano Gambarino, Marta Guariglia, Ilaria Galliano, Massimiliano Bergallo
Format: Artigo
Language:Inglês
Published: MDPI AG 2025-01-01
Series:Cells
Subjects:
irritable bowel syndrome
human endogenous retroviruses
TRIM28
SETDB1
pathogenesis
Online Access:https://www.mdpi.com/2073-4409/14/3/196
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