Tyrphostin AG17 inhibits adipocyte differentiation in vivo and in vitro

Abstract Background Excessive subcutaneous adiposity in obesity is associated to positive white adipocyte tissue (WAT) differentiation (adipogenesis) and WAT expandability. Here, we hypothesized that supplementation with the insulin inhibitor and mitochondrial uncoupler, Tyrphostin (T-AG17), in vitr...

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Principais autores:	Alberto Camacho, Juan Carlos Segoviano-Ramírez, Adriana Sánchez-Garcia, Jose de Jesus Herrera-de la Rosa, Jaime García-Juarez, Carlos Alberto Hernandez-Puente, Geovana Calvo-Anguiano, Sergio Rodolfo Maltos-Uro, Alejandra Olguin, Gabriel Gojon-Romanillos, Gabriel Gojon-Zorrilla, Rocio Ortiz-Lopez
Format:	Artigo
Jezik:	Inglês
Izdano:	BMC 2018-05-01
Serija:	Lipids in Health and Disease
Teme:	Tyrphostin AG17 Adipogenesis Obesity Hepatic steatosis Oxidative phosphorylation
Online dostop:	http://link.springer.com/article/10.1186/s12944-018-0784-7
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