Human Antibodies against Herpes Simplex Virus 2 Glycoprotein G Do Not Neutralize but Mediate Antibody-Dependent Cellular Cytotoxicity

Herpes simplex virus 2 (HSV-2) is a sexually transmitted infection affecting 491 million individuals globally. Consequently, there is a great need for both prophylactic and therapeutic vaccines. Unfortunately, several vaccine clinical trials, primarily employing the glycoprotein D of HSV-2 (gD-2), h...

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Principais autores:	Jan-Åke Liljeqvist, Karin Önnheim, Petra Tunbäck, Kristina Eriksson, Staffan Görander, Malin Bäckström, Tomas Bergström
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-05-01
Series:	Antibodies
Assuntos:	concentrations of anti-gD-2 and anti-EXCT4-mgG-2 antibodies herpes simplex virus 1 and 2 infection neutralization activity ADCC CDC
Acceso en liña:	https://www.mdpi.com/2073-4468/13/2/40
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