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Mutational robustness and the role of buffer genes in evolvability

Abstract Organisms rely on mutations to fuel adaptive evolution. However, many mutations impose a negative effect on fitness. Cells may have therefore evolved mechanisms that affect the phenotypic effects of mutations, thus conferring mutational robustness. Specifically, so-called buffer genes are h...

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Principais autores: Mohammed T Tawfeeq, Karin Voordeckers, Pieter van den Berg, Sander K Govers, Jan Michiels, Kevin J Verstrepen
Formato: Artigo
Idioma:Inglês
Publicado: Springer Nature 2024-05-01
Series:The EMBO Journal
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Acceso en liña:https://doi.org/10.1038/s44318-024-00109-1
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