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Single-cell RNA sequencing reveals Immune Education promotes T cell survival in mice subjected to the cecal ligation and puncture sepsis model

BackgroundIndividual T cell responses vary significantly based on the microenvironment present at the time of immune response and on prior induced T cell memory. While the cecal ligation and puncture (CLP) model is the most commonly used murine sepsis model, the contribution of diverse T cell respon...

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Principais autores: Steven D. Ham, Mabel N. Abraham, Clifford S. Deutschman, Matthew D. Taylor
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2024-03-01
Serier:Frontiers in Immunology
Fag:
cecal ligation and puncture
mouse sepsis model
sepsis
T cell
CD4
CD8
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1366955/full
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