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A Novel Phosphorylated Tau Conformer Implicated in the Tauopathy Pathogenesis of Human Neurons

Alzheimer’s disease (AD) is a neurodegenerative disorder with no effective treatments. Hyperphosphorylation of tau protein contributes to neurodegeneration in AD. Previous studies have identified pT231-tau in the cis conformation as an early driver of neurodegeneration in tauopathy models. Here, we...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Nahid Tofigh, Sadaf Agahi, Gholamhossein Riazi, Mahboobeh Ghalamkar Moazzam, Koorosh Shahpasand
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2025-04-01
Saila:Biomolecules
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/2218-273X/15/4/585
Etiketak: Etiketa erantsi
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