Solubility enhancement of carvedilol using drug–drug cocrystallization with hydrochlorothiazide
Abstract Background Increasing hydrophilicity of poorly water-soluble drugs is a major challenge in drug discovery and development. Cocrystallization is one of the techniques to enhance the hydrophilicity of such drugs. Carvedilol (CAR), a nonselective beta/alpha1 blocker, used in the treatment of m...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SpringerOpen
2020-11-01
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| coleção: | Future Journal of Pharmaceutical Sciences |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s43094-020-00083-5 |
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