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Pharmacokinetic study of Q808 in rhesus monkey using liquid chromatography–tandem mass spectrometry

BackgroundQ808 is a novel antiepileptic agent currently in development. In this study, we established and validated a LC-MS/MS method for the quantification of Q808 in Rhesus monkey plasma. Furthermore, we applied this method to investigate the pharmacokinetics of Q808 in Rhesus monkeys.MethodsSampl...

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Autors principals: Ning Xiao, Xiang Li, Wei Li, Jialin Zhao, Yingnan Li, Limei Wang
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2024-07-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2024.1433043/full
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