In silico quantification of the stiffness perceived by cells inside porous collagen-based scaffolds

Stiffness is a pivotal property of the insoluble matrix surrounding cells, and a known regulator of multiple cell phenotypes. Yet, no universal metric to quantify the stiffness perceived by cells in 3D matrices exists. This manuscript presents a direct metric and efficient in silico method to quanti...

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Bibliografiska uppgifter

Huvudupphov:	Oliver Santos-Lopes, Dimitrios S. Tzeranis, Vasileios Vavourakis
Materialtyp:	Artigo
Språk:	Inglês
Utgiven:	Elsevier 2026-02-01
Serie:	Materials & Design
Ämnen:	Cell-matrix interactions Mechanosensing Porous scaffolds Biomaterial mechanics Finite element method In silico model
Länkar:	http://www.sciencedirect.com/science/article/pii/S0264127525018337
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