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Mitochondrial ROS Accumulation Contributes to Maternal Hypertension and Impaired Remodeling of Spiral Artery but Not IUGR in a Rat PE Model Caused by Maternal Glucocorticoid Exposure

Increased maternal glucocorticoid levels have been implicated as a risk factor for preeclampsia (PE) development. We found that pregnant rats exposed to dexamethasone (DEX) showed hallmarks of PE features, impaired spiral artery (SA) remodeling, and elevated circulatory levels of sFlt1, sEng IL-1β,...

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Autors principals: Jing Long, Yan Huang, Gang Wang, Zhengshan Tang, Yali Shan, Shiping Shen, Xin Ni
Format: Artigo
Idioma:Inglês
Publicat: MDPI AG 2023-04-01
Col·lecció:Antioxidants
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Accés en línia:https://www.mdpi.com/2076-3921/12/5/987
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