A two-stage computational approach to predict novel ligands for a chemosensory receptor
Olfactory receptor (OR) 1A2 is the member of largest superfamily of G protein-coupled receptors (GPCRs). OR1A2 is an ectopically expressed receptor with only 13 known ligands, implicated in reducing hepatocellular carcinoma progression, with enormous therapeutic potential. We have developed a two-st...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2020-01-01
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| Colección: | Current Research in Structural Biology |
| Materias: | |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S2665928X20300210 |
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