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Exploring the therapeutic mechanism of itraconazole combined with ritonavir on Candida albicans infection through network pharmacology and molecular docking

BackgroundAutophagy induced by itraconazole and ritonavir was found involved in the pathogenesis of C. albicans. This study was designed to explore the possible molecular mechanism of itraconazole and ritonavir in the treatment of Candida albicans infection through autophagy pathway.MethodsThe overl...

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Autors principals: Yiyang Feng, Wenli Feng, Jing Yang, Yan Ma
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2025-07-01
Col·lecció:Frontiers in Pharmacology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fphar.2025.1578749/full
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