Simultaneous quantification of donepezil and memantine by HPLC–refractive index detection for novel drug delivery systems
Abstract Alzheimer’s dementia is often treated with a combination of memantine and donepezil, which is more effective than monotherapy. Despite its clinical relevance, simultaneous determination is challenging due to the absence of a chromophore in memantine. Herein, a simple, accurate, and sensitiv...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BMC
2026-05-01
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| Serier: | BMC Chemistry |
| Fag: | |
| Online adgang: | https://doi.org/10.1186/s13065-026-01835-9 |
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