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GPER1 reduces skin inflammation by inhibiting keratinocyte proliferation

Abstract Psoriasis is a chronic inflammatory skin disease characterized by keratinocyte (KC) hyperproliferation and immune cell infiltration, including neutrophils. While estrogens are known to modulate immune responses, the role of the G protein-coupled estrogen receptor 1 (GPER1) in skin inflammat...

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Bibliografische gegevens
Hoofdauteurs: Natalia Pérez-Escudero, Isabel Cabas, Raúl Corbalán-Vélez, Teresa Martínez-Menchón, Belén Ferri, María L. Cayuela, Diana García-Moreno, Alfonsa García-Ayala, Victoriano Mulero
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2026-03-01
Reeks:Cell Death Discovery
Online toegang:https://doi.org/10.1038/s41420-026-03059-1
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