Retinoic Acid Receptors Control Spermatogonia Cell-Fate and Induce Expression of the SALL4A Transcription Factor.

All-trans retinoic acid (ATRA) is instrumental to male germ cell differentiation, but its mechanism of action remains elusive. To address this question, we have analyzed the phenotypes of mice lacking, in spermatogonia, all rexinoid receptors (RXRA, RXRB and RXRG) or all ATRA receptors (RARA, RARB a...

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Detalhes bibliográficos

Principais autores:	Aurore Gely-Pernot, Mathilde Raverdeau, Marius Teletin, Nadège Vernet, Betty Féret, Muriel Klopfenstein, Christine Dennefeld, Irwin Davidson, Gérard Benoit, Manuel Mark, Norbert B Ghyselinck
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2015-10-01
coleção:	PLoS Genetics
Acesso em linha:	http://europepmc.org/articles/PMC4591280?pdf=render
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