Actin networks modulate heterogeneous NF-κB dynamics in response to TNFα

The canonical NF-κB transcription factor RELA is a master regulator of immune and stress responses and is upregulated in pancreatic ductal adenocardinoma (PDAC) tumours. In this study, we characterised previously unexplored endogenous RELA-GFP dynamics in PDAC cell lines through live single-cell ima...

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Detalles Bibliográficos

Principais autores:	Francesca Butera, Julia E Sero, Lucas G Dent, Chris Bakal
Formato:	Artigo
Idioma:	Inglês
Publicado:	eLife Sciences Publications Ltd 2024-08-01
Series:	eLife
Assuntos:	actin NF-κB RELA PDAC single-cell dynamics TNF
Acceso en liña:	https://elifesciences.org/articles/86042
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