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Developmental emergence of sparse and structured synaptic connectivity in the hippocampal CA3 memory circuit

Abstract Hippocampal CA3 pyramidal neurons (PNs) form the largest autoassociative network in the mammalian brain. Whether CA3–CA3 recurrent connectivity is genetically preconfigured or environmentally shaped during ongoing memory storage is currently unknown. To address this question, we performed m...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Victor Vargas-Barroso, Jake F. Watson, Andrea Navas-Olive, Alois Schlögl, Peter Jonas
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2026-04-01
Rangatū:Nature Communications
Urunga tuihono:https://doi.org/10.1038/s41467-026-71914-x
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