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Effective Perturbations by Phenobarbital on <i>I</i><sub>Na</sub>, <i>I</i><sub>K(erg)</sub>, <i>I</i><sub>K(M)</sub> and <i>I</i><sub>K(DR)</sub> during Pulse Train Stimulation in Neuroblastoma Neuro-2a Cells

Phenobarbital (PHB, Luminal Sodium<sup>®</sup>) is a medication of the barbiturate and has long been recognized to be an anticonvulsant and a hypnotic because it can facilitate synaptic inhibition in the central nervous system through acting on the γ-aminobutyric acid (GABA) type A (GABA<sub>A</sub>...

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Principais autores: Po-Ming Wu, Pei-Chun Lai, Hsin-Yen Cho, Tzu-Hsien Chuang, Sheng-Nan Wu, Yi-Fang Tu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-08-01
coleção:Biomedicines
Assuntos:
phenobarbital (phenobarbitone, Luminal Sodium<sup>®</sup>)
voltage-gated Na<sup>+</sup> current
<i>erg</i>-mediated K<sup>+</sup> current
M-type K<sup>+</sup> current
delayed-rectifier K<sup>+</sup> current
pulse train stimulation
Acesso em linha:https://www.mdpi.com/2227-9059/10/8/1968
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