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SWI/SNF complexes act through CBP-1 histone acetyltransferase to regulate acute functional tolerance to alcohol

Abstract Background SWI/SNF chromatin remodeling genes are required for normal acute responses to alcohol in C. elegans and are associated with alcohol use disorder in two human populations. In an effort to discover the downstream genes that are mediating this effect, we identified SWI/SNF-regulated...

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Principais autores: Laura D. Mathies, Jonathan H. Lindsay, Amal P. Handal, GinaMari G. Blackwell, Andrew G. Davies, Jill C. Bettinger
格式: Artigo
语言:Inglês
出版: BMC 2020-09-01
丛编:BMC Genomics
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在线阅读:http://link.springer.com/article/10.1186/s12864-020-07059-y
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