TrCla4 promotes actin polymerization at the hyphal tip and mycelial growth in Trichophyton rubrum

ABSTRACT Dermatophytes invade and colonize host superficial tissues via hyphal growth. Although cytoskeletal reorganization and its regulation are essential for hyphal growth, the molecular mechanisms in dermatophytes and their applicability as antifungal drug targets remain poorly understood. The p...

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Hlavní autoři:	Masaki Ishii, Yasuhiko Matsumoto, Tsuyoshi Yamada, Hideko Uga, Toshiaki Katada, Shinya Ohata
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2023-12-01
Edice:	Microbiology Spectrum
Témata:	dermatophytosis p21-activated kinase PAK inhibitor IPA-3 actin polymerization Trichophyton rubrum
On-line přístup:	https://journals.asm.org/doi/10.1128/spectrum.02923-23
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