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PPARγ attenuates cellular senescence of alveolar macrophages in asthma-COPD overlap

Abstract Background Asthma-chronic obstructive pulmonary disease (COPD) overlap (ACO) represents a complex condition characterized by shared clinical and pathophysiological features of asthma and COPD in older individuals. However, the pathophysiology of ACO remains unexplored. We aimed to identify...

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Principais autores: Rongjun Wan, Prakhyath Srikaram, Shaobing Xie, Qiong Chen, Chengping Hu, Mei Wan, Yuanyuan Li, Peisong Gao
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-04-01
coleção:Respiratory Research
Assuntos:
ACO
Asthma
COPD
Macrophages
Senescence
PPARγ
Acesso em linha:https://doi.org/10.1186/s12931-024-02790-6
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