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Peripheral Precocious Puberty of Ovarian Origin in a Series of 18 Girls: Exome Study Finds Variants in Genes Responsible for Hypogonadotropic Hypogonadism

Background: Peripheral precocious puberty of ovarian origin is a very rare condition compared to central form. It may be associated with an isolated ovarian cyst (OC). The causes of OC in otherwise healthy prepubertal girls is currently unknown.Methods: Exome sequencing was performed on a cohort of...

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Principais autores: Raja Brauner, Joelle Bignon-Topalovic, Anu Bashamboo, Ken McElreavey
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-05-01
coleção:Frontiers in Pediatrics
Assuntos:
genetic variant
hypogonadotropic hypogonadism
ovarian cyst
precocious puberty
prenatal ovarian cyst
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fped.2021.641397/full
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