TLR4/Inflammasomes Cross-Talk and Pyroptosis Contribute to N-Acetyl Cysteine and Chlorogenic Acid Protection against Cisplatin-Induced Nephrotoxicity

Background: Cisplatin (Cp) is an antineoplastic agent with a dose-limiting nephrotoxicity. Cp-induced nephrotoxicity is characterized by the interplay of oxidative stress, inflammation, and apoptosis. Toll-4 receptors (TLR4) and NLPR3 inflammasome are pattern-recognition receptors responsible for ac...

Descrición completa

Detalles Bibliográficos

Principais autores:	Amira M. Badr, Layla A. Al-Kharashi, Hala Attia, Samiyah Alshehri, Hanaa N. Alajami, Rehab A. Ali, Yasmen F. Mahran
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-02-01
Series:	Pharmaceuticals
Assuntos:	cisplatin nephrotoxicity TLR4 inflammasomes NLPR3 N-acetylcysteine
Acceso en liña:	https://www.mdpi.com/1424-8247/16/3/337
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!