Exploring the selectivity and engineering potential of an NRPS condensation domain involved in the biosynthesis of the thermophilic siderophore fuscachelin

In nonribosomal peptide synthesis, condensation (C) domains are key catalytic domains that most commonly link carrier protein bound substrates to form peptides or depsipeptides. While adenylation domains have been well characterized due to their role in the selection of monomers and hence as gate ke...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Y. T. Candace Ho, Thierry Izoré, Joe A. Kaczmarski, Edward Marschall, Minuri S. Ratnayake, Julien Tailhades, David L. Steer, Ralf B. Schittenhelm, Manuela Tosin, Colin J. Jackson, Max J. Cryle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2023-06-01
coleção:	Frontiers in Catalysis
Assuntos:	nonribosomal peptide (NRP) biosynthesis condensation domain peptidyl carrier protein biocatalysis depsipeptide
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fctls.2023.1184959/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!