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Novel sulphonamides incorporating triazene moieties show powerful carbonic anhydrase I and II inhibitory properties

A series of compounds incorporating 3-(3-(2/3/4-substituted phenyl)triaz-1-en-1-yl) benzenesulfonamide moieties were synthesised and their chemical structure was confirmed by physico-chemical methods. Carbonic anhydrase (CA, EC 4.2.1.1) inhibitory effects of the compounds were evaluated against huma...

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Principais autores: Sinan Bilginer, Baris Gonder, Halise Inci Gul, Ruya Kaya, Ilhami Gulcin, Baris Anil, Claudiu T. Supuran
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-01-01
coleção:Journal of Enzyme Inhibition and Medicinal Chemistry
Assuntos:
Acesso em linha:http://dx.doi.org/10.1080/14756366.2019.1700240
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