Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity

Cerebellar plasticity underlies motor learning. However, how the cerebellum operates to enable learned changes in motor output is largely unknown. We developed a sensory-driven adaptation protocol for reflexive whisker protraction and recorded Purkinje cell activity from crus 1 and 2 of awake mice....

ver descrição completa

Detalhes bibliográficos

Principais autores:	Vincenzo Romano, Licia De Propris, Laurens WJ Bosman, Pascal Warnaar, Michiel M ten Brinke, Sander Lindeman, Chiheng Ju, Arthiha Velauthapillai, Jochen K Spanke, Emily Middendorp Guerra, Tycho M Hoogland, Mario Negrello, Egidio D'Angelo, Chris I De Zeeuw
Formato:	Artigo
Idioma:	Inglês
Publicado em:	eLife Sciences Publications Ltd 2018-12-01
coleção:	eLife
Assuntos:	plasticity learning motor control cerebellum whiskers Purkinje cell
Acesso em linha:	https://elifesciences.org/articles/38852
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!