Absolute Quantification of Hepatitis B Core Antigen (HBcAg) Virus-like Particles and Bound Nucleic Acids

Effective process development towards intensified processing for gene delivery applications using Hepatitis B core Antigen (HBcAg) virus-like particles (VLPs) relies on analytical methods for the absolute quantification of HBcAg VLP proteins and bound nucleic acids. We investigated a silica spin col...

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Autors principals:	Angela Valentic, Nicola Böhner, Jürgen Hubbuch
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-12-01
Col·lecció:	Viruses
Matèries:	virus-like particles nucleic acid extraction silica spin column RP-HPLC HBcAg analytical characterization
Accés en línia:	https://www.mdpi.com/1999-4915/16/1/13
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