Revisiting CD8 T-cell ‘Memory Inflation’: New Insights with Implications for Cytomegaloviruses as Vaccine Vectors

Murine models of cytomegalovirus (CMV) infection have revealed an exceptional kinetics of the immune response. After resolution of productive infection, transient contraction of the viral epitope-specific CD8 T-cell pool was found to be followed by a pool expansion specific for certain viral epitope...

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Prif Awduron:	Rafaela Holtappels, Kirsten Freitag, Angelique Renzaho, Sara Becker, Niels A.W. Lemmermann, Matthias J. Reddehase
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	MDPI AG 2020-07-01
Cyfres:	Vaccines
Pynciau:	avidity maturation central memory CD8 T cells (TCM) cytomegalovirus effector memory CD8 T cells (TEM) conventional TEM (cTEM) inflationary TEM (iTEM)
Mynediad Ar-lein:	https://www.mdpi.com/2076-393X/8/3/402
Tagiau:	Ychwanegu Tag Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!