Why Ortho- and Para-Hydroxy Metabolites Can Scavenge Free Radicals That the Parent Atorvastatin Cannot? Important Pharmacologic Insight from Quantum Chemistry

The pharmaceutical success of atorvastatin (ATV), a widely employed drug against the “bad” cholesterol (LDL) and cardiovascular diseases, traces back to its ability to scavenge free radicals. Unfortunately, information on its antioxidant properties is missing or unreliable. Here, we report detailed...

Ausführliche Beschreibung

Bibliografische Detailangaben

1. Verfasser:	Ioan Bâldea
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2022-08-01
Schriftenreihe:	Molecules
Schlagworte:	radical-scavenging activity atorvastatin antioxidant mechanisms HAT SPLET SET-PT
Online-Zugang:	https://www.mdpi.com/1420-3049/27/15/5036
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