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Smart Approach for the Design of Highly Selective Aptamer-Based Biosensors

Aptamers are chemically synthesized single-stranded DNA or RNA oligonucleotides widely used nowadays in sensors and nanoscale devices as highly sensitive biorecognition elements. With proper design, aptamers are able to bind to a specific target molecule with high selectivity. To date, the systemati...

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Principais autores: Ali Douaki, Denis Garoli, A. K. M. Sarwar Inam, Martina Aurora Costa Angeli, Giuseppe Cantarella, Walter Rocchia, Jiahai Wang, Luisa Petti, Paolo Lugli
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-07-01
Serier:Biosensors
Fag:
aptamer
aptasensor
biosensor
machine learning
molecular dynamic simulation
in silico design
Online adgang:https://www.mdpi.com/2079-6374/12/8/574
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