The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease

Abstract The metal ion transporter SLC39A8 is associated with physiological traits and diseases, including blood manganese (Mn) levels and inflammatory bowel diseases (IBD). The mechanisms by which SLC39A8 controls Mn homeostasis and epithelial integrity remain elusive. Here, we generate Slc39a8 int...

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Autors principals:	Eun-Kyung Choi, Thekkelnaycke M. Rajendiran, Tanu Soni, Jin-Ho Park, Luisa Aring, Chithra K. Muraleedharan, Vicky Garcia-Hernandez, Nobuhiko Kamada, Linda C. Samuelson, Asma Nusrat, Shigeki Iwase, Young Ah Seo
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-06-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-024-49049-8
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