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Clonality analysis and IDH1 and IDH2 mutation detection in both components of dedifferentiated chondrosarcoma, implicated its monoclonal origin

Dedifferentiated chondrosarcoma (DDCS) is a highly malignant tumor that belongs to an uncommon subtype of chondrosarcoma with a poor prognosis. Microscopically, it is composed of highly differentiated chondrosarcoma and highly malignant noncartilaginous sarcomas with an abrupt interface. The questio...

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Principais autores: Tingting Yang, Yueqing Bai, Jie Chen, Keyang Sun, Yanli Luo, Wentao Huang, Huizhen Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020-06-01
coleção:Journal of Bone Oncology
Assuntos:
Dedifferentiated chondrosarcoma
Clonality analysis
Origin
IDH1 and IDH2
Mutation
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2212137420300488
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