Pilot evaluation of optical genome mapping in chronic lymphocytic leukemia: complementing FISH analysis

Abstract Background The clinical heterogeneity observed in chronic lymphocytic leukemia (CLL) is largely attributed to diverse underlying genomic alterations. Fluorescence in situ hybridization (FISH) remains the standard cytogenetic technique but is limited to predefined loci. As a genome-wide appr...

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Opis bibliograficzny

Główni autorzy:	Simge Erdem, Ayşe Gül Bayrak Tokaç, Aynur Aday, Dilan Karaca, Mehmet Burak Mutlu, Kıvanç Çefle, Mustafa Nuri Yenerel, Şükrü Öztürk, Sevgi Kalayoğlu Beşışık
Format:	Artigo
Język:	Inglês
Wydane:	BMC 2025-11-01
Seria:	BMC Cancer
Hasła przedmiotowe:	Chronic lymphocytic leukemia Fluorescence in situ hybridization Genome mapping Genomic structural variants
Dostęp online:	https://doi.org/10.1186/s12885-025-15140-6
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