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The Human Cytomegalovirus Major Immediate-Early Proteins as Antagonists of Intrinsic and Innate Antiviral Host Responses

The major immediate-early (IE) gene of human cytomegalovirus (CMV) is believed to have a decisive role in acute infection and its activity is an important indicator of viral reactivation from latency. Although a variety of gene products are expressed from this region, the 72-kDa IE1 and the 86-kDa I...

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Principais autores: Michael Nevels, Christina Paulus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2009-11-01
coleção:Viruses
Assuntos:
cytomegalovirus
CMV
innate immunity
intrinsic defense
interferon response
nuclear domain 10
apoptosis
immediate-early genes
IE1
IE2
Acesso em linha:http://www.mdpi.com/1999-4915/1/3/760/
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